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Latest News and Updates
FDA approves Libre Duo - The worlds first dual glucose and ketone monitor
News & Updates
FDA Clears Libre Duo: The World’s First Dual Glucose & Ketone Monitor
In India, around 77 million people aged 18 and above are suffering from type 2 diabetes. Another alarming fact is that around 25 million are prediabetic, as of a recent report, and are at higher risk of developing diabetes in the near future. More than 50% are unaware of their diabetes status (1). Diabetic ketoacidosis (DKA) remains an important acute complication of diabetes in India, occurring predominantly in people with type 1 diabetes but also affecting those with type 2
Dr. Manisha Dadlani
12 hours ago
FDA Approves First in Class FcRn Blocker IMAAVY (Nipocalimab aahu) for Warm Autoimmune Hemolytic Anemia
On August 24, 2026, the U.S. Food and Drug Administration approved Janssen Biotech’s IMAAVY (nipocalimab-aahu) injection for adult and pediatric patients aged 12 years and older currently or previously treated with corticosteroids (1,2). This landmark decision represents the first therapy proven safe and effective specifically for warm autoimmune hemolytic anaemia (wAIHA). As a first-in-class treatment, IMAAVY offers clinical management for an underserved community that has h
Dr. Manisha Dadlani
7 days ago
Daraxonrasib: Restoring Hope in Pancreatic Cancer Management
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most difficult challenges in modern oncology. It is a condition characterised by aggressive tumour growth and a high mortality rate, with a five-year survival rate that persists below 13% (1). Because the disease is often asymptomatic in its early stages, the majority of patients are diagnosed only after the cancer has become metastatic and unresectable. While this mutation drives the disease, the RAS protein was long
Dr. Manisha Dadlani
Aug 31
Clinical Trials & Drug Cards
Secukinumab (Cosentyx®)
Drug class: Interleukin-17A antagonist (1) Mechanism of Action Secukinumab is a targeted biologic therapy designed to interrupt key pathways in inflammatory diseases. It works by binding to interleukin 17A (IL 17A), a cytokine central to the inflammatory process. By blocking IL 17A from interacting with its receptor on keratinocytes and other cell types, secukinumab neutralizes this signaling pathway. This inhibition reduces the downstream inflammatory cascade that drives pla
Dr. Sheeba Rani
5 days ago
Atezolizumab (Tecentriq)
Drug class: Immune checkpoint inhibitors (PD-L1 inhibitor) Mechanism of Action Atezolizumab is a humanized monoclonal antibody that blocks programmed death ligand 1 (PD L1). Normally, PD L1 binds to tumour-specific T cell receptors, suppressing immune activity and preventing tumour destruction (1,2). As an immune checkpoint inhibitor, atezolizumab reactivates the immune response by binding PD-L1 on cancer cell surfaces, promoting tumour cell elimination. It is approved for mu
Dr. Jaimee George
5 days ago
Ustekinumab (STELARA®)
Drug class: CDK4/6 inhibitor Mechanism of Action Interleukin 12 (IL 12) and interleukin 23 (IL 23) are key drivers of chronic inflammation. Ustekinumab, a fully human immunoglobulin G1 (IgG1) monoclonal antibody, targets the p40 subunit shared by IL 12 and IL 23 heterodimers. By blocking this subunit, ustekinumab prevents IL 12/IL 23 binding to the IL 12 receptor β1 (IL 12Rβ1) on immune cell surfaces. This inhibition disrupts downstream differentiation and activation of T hel
Dr. Jaimee George
6 days ago
Spotlight
Clinical Spotlight: Flonase Nasal Spray for Rhinitis Management
Chronic inflammatory diseases of the nasal mucosa such as allergic rhinitis, rhinosinusitis, and nasal polyposis pose a significant clinical burden but can be effectively managed with topically active corticosteroids (1,2). Allergic rhinitis is a chronic inflammatory disorder of the nasal mucosa triggered by environmental allergens (1). Allergic rhinitis is highly prevalent in India, with recent large‑scale studies showing that more than half of patients presenting with nasal
Dr. Manisha Dadlani
Sep 1
Prenatal care spotlight: The double marker test.
1. Overview The double marker test is a crucial prenatal assessment tool used during the first trimester of pregnancy. Its main purpose is to detect pregnancies that are at elevated risk for the onset of chromosomal disorders. The test integrates maternal age with particular biochemical indicators to evaluate fetal well-being (1). The double marker test, also known as the double test, measures two serum markers: free beta-human chorionic gonadotropin (free beta-hCG) and pregn
Dr. Manisha Dadlani
Apr 21
Inclisiran - A game changer in ASCVD management
Atherosclerotic cardiovascular disease (ASCVD) is amongst the leading causes of death worldwide, accounting for an estimated 19 million deaths each year (1). The mortality rates are even higher in India linked with an earlier age of onset and greater severity of the disease (2,3). More than half of cardiac deaths in India occur below the age of 50 years and 25% occur below the age of 40 years. The skyrocketing rates are due to a combination of risk factors which include dysli
Dr. Geetika Gupta
Sep 10, 2025
Patient Stories & Patient Education Literature
My experience with Freestyle Libre2 Plus for continuous glucose monitoring
I was diagnosed with diabetes in 2024. My doctor initially prescribed Metformin, but I couldn’t tolerate it. Later, I was shifted to Vildagliptin. For a while, things seemed fine, so I didn’t pay much attention. A year later, routine blood tests shocked me. My HbA1c was 8%, despite being on medication. That was the wake‑up call. I consulted my doctor again, who suggested a change in medication along with diet and lifestyle measures to get things under control. Since I already
Ramesh Mylapilli
3 days ago
Living with Psoriasis: Your Guide to Skin Confidence
Do you struggle with dry, flaky, or irritated skin that never seems to improve? Are flare ups leaving you frustrated or making you feel like you need to hide your skin? You may be dealing with psoriasis, a common condition that affects both skin and confidence. By understanding what psoriasis is, its symptoms, and how it can be managed, you can take meaningful steps toward healthier skin and overall, well-being. What Is Psoriasis? Psoriasis is a long-term skin condition tha
Ms. Mohana Ragavi
5 days ago
Urinary Incontinence Explained: Symptoms, Causes and Care
Sanjay, a 47‑year‑old IT professional, led a sedentary lifestyle with long working hours and little physical activity. Over the past few months, he began experiencing unexpected urine leakage, especially when laughing loudly or sneezing. With no prior health issues, these episodes left him confused and frustrated. After repeated incidents, he finally consulted his physician. Rekha, a 30‑year‑old mother of a two‑year‑old, faced similar challenges. Along with leakage, she frequ
Dr. Kaveri Purandhar
Aug 27
Case Reports
Management of Gastroesophageal Reflux Disease in a Middle‑Aged Male with Helicobacter pylori Infection
History A 48‑year‑old male presented with retrosternal burning persisting for ~5 years, initially 1–2 times per week post‑prandially, now occurring daily and nocturnally. Associated symptoms included cough, regurgitation, acidic taste, postprandial fullness, and early satiety, worsened by spicy food, bending, or lying flat. Sleep was significantly disturbed. He reported recurrent shortness of breath over 4 years, diagnosed as bronchitis, with severe cough episodes often stre
Dr. Sheeba Rani
8 hours ago
Acute decompensated heart failure in a 56-year old female patient with hypertension, type-2 diabetes, and hyperlipidemia: A clinical case report.
Abstract This is a case of a 56-year-old woman who has had high blood pressure for 8 years, type 2 diabetes for 6 years, and high cholesterol. She started experiencing worse symptoms, including trouble breathing when active and even when resting, difficulty breathing while lying down, sudden nighttime breathing problems, a dry cough, tiredness, a 3 kg weight gain, and mild chest pain. The initial evaluation of the cardiovascular examination revealed JVD (jugular vein distensi
Ms. Pallavi Mukku
Mar 14
Managing Enteric Fever in a 24-year old patient
A 24-year-old female presented to the outpatient clinic with a two-week history of high-grade fever accompanied by generalized myalgia, fatigue, severe frontal headache, and watery, non-bloody diarrhea occurring three to five times daily. She also reported poor appetite, progressive weakness, and noticed brownish pigmentation in urine over the preceding few days. The symptoms had initially begun with abdominal pain and headache before progressively worsening. The patient had
Ms. Hima Saxena
Sep 8, 2025
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