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Latest News and Updates
FDA approves Libre Duo - The worlds first dual glucose and ketone monitor
News & Updates
Upcoming Medical Congresses
American College of surgeons - Clinical Congress 2026 Date of event: September 26–29,2026 Location: Washington, DC The conference provides a premier professional development forum for the global surgical community, bringing together renowned surgeons, researchers, and healthcare professionals to explore the latest advances in surgical science and clinical practice. Focused on translating groundbreaking research and innovative procedures into real-world patient care, the event
Ms. Vidya Kalyani
10 hours ago
FDA Approves Rusfertide, the First-in-Class Hepcidin Mimetic for Polycythemia Vera
Polycythemia vera is a chronic myeloproliferative neoplasm characterized by abnormal overproduction of red blood cells, resulting in erythrocytosis (1,2). This excess red blood cell production increases hematocrit, the proportion of red blood cells relative to total blood volume, thereby increasing blood viscosity. In the United States, PV affects an estimated 90,000 individuals (2). Elevated blood viscosity associated with uncontrolled hematocrit increases the risk of seriou
Dr. Manisha Dadlani
12 hours ago
FDA Approves Tirzepatide to Reduce Cardiovascular Risk in Adults with Type 2 Diabetes
Cardiovascular disease remains a major cause of morbidity and mortality among people with type 2 diabetes. Epidemiological studies estimate that as many as one in three U.S. adults with type 2 diabetes have undetected subclinical cardiovascular disease (1). David A. D’Alessio, Director of Endocrinology and Metabolism at Duke University School of Medicine, emphasized that “heart health deserves attention throughout the course of treatment, not just after a serious cardiovascul
Dr. Manisha Dadlani
13 hours ago
Clinical Trials & Drug Cards
Apixaban (Eliquis)
Drug class: Direct, selective Factor Xa inhibitor (1,2) Mechanism of Action The coagulation cascade consists of two main pathways: the intrinsic and extrinsic pathways. The extrinsic pathway is activated when vascular injury exposes tissue factor (TF), which binds to and activates factor VII; the resulting TF–factor VIIa complex then activates factor X to factor Xa. The extrinsic pathway provides rapid initiation of coagulation (3). Vascular trauma triggers platelet activati
Padmashobana Bagavathithasan
11 hours ago
Secukinumab (Cosentyx®)
Drug class: Interleukin-17A antagonist (1) Mechanism of Action Secukinumab is a targeted biologic therapy designed to interrupt key pathways in inflammatory diseases. It works by binding to interleukin 17A (IL 17A), a cytokine central to the inflammatory process. By blocking IL 17A from interacting with its receptor on keratinocytes and other cell types, secukinumab neutralizes this signaling pathway. This inhibition reduces the downstream inflammatory cascade that drives pla
Dr. Sheeba Rani
6 days ago
Atezolizumab (Tecentriq)
Drug class: Immune checkpoint inhibitors (PD-L1 inhibitor) Mechanism of Action Atezolizumab is a humanized monoclonal antibody that blocks programmed death ligand 1 (PD L1). Normally, PD L1 binds to tumour-specific T cell receptors, suppressing immune activity and preventing tumour destruction (1,2). As an immune checkpoint inhibitor, atezolizumab reactivates the immune response by binding PD-L1 on cancer cell surfaces, promoting tumour cell elimination. It is approved for mu
Dr. Jaimee George
6 days ago
Spotlight
Clinical Spotlight: Flonase Nasal Spray for Rhinitis Management
Chronic inflammatory diseases of the nasal mucosa such as allergic rhinitis, rhinosinusitis, and nasal polyposis pose a significant clinical burden but can be effectively managed with topically active corticosteroids (1,2). Allergic rhinitis is a chronic inflammatory disorder of the nasal mucosa triggered by environmental allergens (1). Allergic rhinitis is highly prevalent in India, with recent large‑scale studies showing that more than half of patients presenting with nasal
Dr. Manisha Dadlani
Sep 1
Prenatal care spotlight: The double marker test.
1. Overview The double marker test is a crucial prenatal assessment tool used during the first trimester of pregnancy. Its main purpose is to detect pregnancies that are at elevated risk for the onset of chromosomal disorders. The test integrates maternal age with particular biochemical indicators to evaluate fetal well-being (1). The double marker test, also known as the double test, measures two serum markers: free beta-human chorionic gonadotropin (free beta-hCG) and pregn
Dr. Manisha Dadlani
Apr 21
Inclisiran - A game changer in ASCVD management
Atherosclerotic cardiovascular disease (ASCVD) is amongst the leading causes of death worldwide, accounting for an estimated 19 million deaths each year (1). The mortality rates are even higher in India linked with an earlier age of onset and greater severity of the disease (2,3). More than half of cardiac deaths in India occur below the age of 50 years and 25% occur below the age of 40 years. The skyrocketing rates are due to a combination of risk factors which include dysli
Dr. Geetika Gupta
Sep 10, 2025
Patient Stories & Patient Education Literature
My experience with Freestyle Libre2 Plus for continuous glucose monitoring
I was diagnosed with diabetes in 2024. My doctor initially prescribed Metformin, but I couldn’t tolerate it. Later, I was shifted to Vildagliptin. For a while, things seemed fine, so I didn’t pay much attention. A year later, routine blood tests shocked me. My HbA1c was 8%, despite being on medication. That was the wake‑up call. I consulted my doctor again, who suggested a change in medication along with diet and lifestyle measures to get things under control. Since I already
Ramesh Mylapilli
4 days ago
Living with Psoriasis: Your Guide to Skin Confidence
Do you struggle with dry, flaky, or irritated skin that never seems to improve? Are flare ups leaving you frustrated or making you feel like you need to hide your skin? You may be dealing with psoriasis, a common condition that affects both skin and confidence. By understanding what psoriasis is, its symptoms, and how it can be managed, you can take meaningful steps toward healthier skin and overall, well-being. What Is Psoriasis? Psoriasis is a long-term skin condition tha
Ms. Mohana Ragavi
6 days ago
Urinary Incontinence Explained: Symptoms, Causes and Care
Sanjay, a 47‑year‑old IT professional, led a sedentary lifestyle with long working hours and little physical activity. Over the past few months, he began experiencing unexpected urine leakage, especially when laughing loudly or sneezing. With no prior health issues, these episodes left him confused and frustrated. After repeated incidents, he finally consulted his physician. Rekha, a 30‑year‑old mother of a two‑year‑old, faced similar challenges. Along with leakage, she frequ
Dr. Kaveri Purandhar
Aug 27
Case Reports
Management of Gastroesophageal Reflux Disease in a Middle‑Aged Male with Helicobacter pylori Infection
History A 48‑year‑old male presented with retrosternal burning persisting for ~5 years, initially 1–2 times per week post‑prandially, now occurring daily and nocturnally. Associated symptoms included cough, regurgitation, acidic taste, postprandial fullness, and early satiety, worsened by spicy food, bending, or lying flat. Sleep was significantly disturbed. He reported recurrent shortness of breath over 4 years, diagnosed as bronchitis, with severe cough episodes often stre
Dr. Sheeba Rani
1 day ago
Acute decompensated heart failure in a 56-year old female patient with hypertension, type-2 diabetes, and hyperlipidemia: A clinical case report.
Abstract This is a case of a 56-year-old woman who has had high blood pressure for 8 years, type 2 diabetes for 6 years, and high cholesterol. She started experiencing worse symptoms, including trouble breathing when active and even when resting, difficulty breathing while lying down, sudden nighttime breathing problems, a dry cough, tiredness, a 3 kg weight gain, and mild chest pain. The initial evaluation of the cardiovascular examination revealed JVD (jugular vein distensi
Ms. Pallavi Mukku
Mar 14
Managing Enteric Fever in a 24-year old patient
A 24-year-old female presented to the outpatient clinic with a two-week history of high-grade fever accompanied by generalized myalgia, fatigue, severe frontal headache, and watery, non-bloody diarrhea occurring three to five times daily. She also reported poor appetite, progressive weakness, and noticed brownish pigmentation in urine over the preceding few days. The symptoms had initially begun with abdominal pain and headache before progressively worsening. The patient had
Ms. Hima Saxena
Sep 8, 2025
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